B-Cell Development and Activation

This week’s blog is a bit of a departure from classical clinical microbiology and into the world of immunology. I feel as though microbiology is inextricably linked to immunology. Plus, B-cells are just really cool. B-cell development is very complex and involves genetic mutations/ rearrangements, alternate RNA splicing, cell signaling, tertiary structural interactions, and DNA excision. I can’t think of a better bridge between microbiology, molecular biology, biochemistry, cell biology, and immunology. I hope you enjoy this figure—I’ll see you next week.

One of my former students asked me for help with their biology final exam so of course I remixed @theestallion's Body song into #Antibodyody to teach a little about antibodies and the immune response. A quick little song from your favorite scientist #body 😂 pic.twitter.com/ElFayiCAwd

— Raven the Science Maven (@ravenscimaven) November 27, 2020